ILK-affixinŠΦ˜A@”­•\˜_•Ά
   
   
   
  2001”N Yamaji S, Suzuki A, Sugiyama Y, Koide Y, Yoshida M, Kanamori H, Mori H, Ohno S, Ishigatubo Y*.
A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction. J.Cell Biol. 153: 1251-1264, 2001
     
  2002”N Yamaji S, Suzuki A, Kanamori H, Mishima W, Takabayashi M, Fujimaki K, Tomita N, Fujisawa S, Ohno S, Ishigatsubo Y*.
Possble role of ILK-affixin complex in integrin-cytoskeleton linkage during platelet aggregation. Biochem. Biophys. Res. Commun. 297: 1324- 1331, 2002
     
  2004”N Yamaji S, Suzuki A, Kanamori H, Mishima W, Yoshimi R, Takasaki H, Takabayashi M, Fujimaki K, Fujisawa S, Ohno S, Ishigatsubo Y*.
Affixin interacts with a-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction. J. Cell. Biol. 165: 539-551, 2004
     
    Mishima W, Suzuki A, Yamaji S, Yoshimi R, Ueda A, Kaneko T, Tanaka J, Miwa Y, Ohno S, Ishigatsubo Y*.
The first CH domain of affixin activates Cdc42 and Rac1 through ƒΏPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor. Genes to Cells 9: 193-204, 2004
     
  2005”N  Matsuda C, Kameyama K, Tagawa K, Ogawa M, Suzuki A, Yamaji S, Okamoto H, Nishino I, Hayashi Y.K*.
Dysferlin interacts with affixin (gamma-parvin) at the sarcolemma. J. Neuropathol. Exp. Neurol. 64: 334-340, 2005
     
  2006”N  Yoshimi R, Yamaji S, Suzuki A, Mishima W, Okamura M, Obana T, Matsuda C, Miwa Y, Ohno S, Ishigatsubo Y*.
The gamma-parvin-integrin-linked kinase complex is critically involved in leukocyte-substrate interaction.

J. Immunol.
176: 3611-3624, 2006
     
  2008”N Matsuda C, Kameyama K, Suzuki A, Mishima W, Yamaji S, Okamoto H, Nishino I, Hayashi Y.K*.
Affixin activate Rac1 via betaPIX in C2C12 myoblast. FEBS Lett. 582: 1189-1196, 2008